Why the application goes unresponsive often, though the CPU time utilization is high?

Why the application goes unresponsive often, though the CPU time utilization is high?

Due to some processes running in the background. For example, When some measures are not found in any of the graphs defined in the dashboard, the system goes into an endless loop, searching for them. Post identification rectify those measures. If any further help consult with support team on this.